DEF
DISEASE STATE CHARACTERISED BY CHRONIC AIR FLOW LIMITATION WITHOUT FULL REVERSIBlity
CLASSIFICATION
1 CHRONIC bronchitis ( Cb )
a simple
b chr mucoplurlent
c chr obstructive
2 emphysema ( Em )
a centriacinar
b panacinar
ETIO
1 SMOKING
2 AIR POLLUTION
3 INFECTIO
4 OCCUPATION
5 GENETIC. Alpha trypsin def
Pathgenesis
1 hypertropy of br mucous gland
2 lead to more mucous secretion
3 lead to cilliary activity inhibition
4 lead to collectio of mucous
5 lead to infectio and inflam
6 lead t o destructio of br elastic tissue
7 lead to collaps of small airway obstruction and dil of alveoli.
C/f
1 cough with expect
2 dyspnea
3 wheez
4 smoker cough or morning cough:- :-)mild increase in winter
:-)frequent exacerbating
:-)long duration
:-)hypoxemia lead to resp failure and cor pul
5 purse lip breathing
6 acessory mus working
7 cynosis i.e blue blotter in Cb and
8 pink puffer in Em
9 tremors flapping
10 confusion
11 barrel sh chest
12 sub costal widening
13 hyperesonance
14 ronchi
15 wheze
16 prolong expiratio
17 in ccf loud p2
Investisation
1 pul fun test
air flow limitation fev1 <70%
2 cxR HYPERlucent lung zone
flat diaphram and
tubular heart
3 in act exacerbation ecg show ccf change
4 sputum for gram st . Culture
5 ABG
TREATMENT
A>SHORT TERM
1 low dose o2
2 antibiotic iv amphicillin
3 beta 2 agonist salbutamol
4 aminophili
5 corticosteroid
6 diuretics for ccf
7 anal diazepam
8 ventilator
B>Longterm
1 stop smoking
2 salmetrol inhaler
3 inhal steroid
4 pul rehabil
5 mucolytic
6 long term o2 therapy
7 surgery
Complication
1 recurrent exacerbation
2 rs failure
3 cor pul
4 ccf
5 pneumothorx
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