Narcolepsy:
It is a disorder charactorised by excessive day time sleepiness, often disturbed night time sleep and disturbances in the REM sleep.
Decrease REM latency is the hallmark; REM sleep occures within 10 mins of onset of sleep.
Common age of onset is 15-25 yrs and continues thoughout the life.
Tetrad of symptoms:
1) sleep attacks:
- Person is unable to resist a sleep (nap)
- attack occures during nytime of the day
- gap of 2-35hrs betn two naps
2) cataplexy:
- char' by loss of muscle tone in various parts of body. e.g. Drop jaw
- may b precipited by sudden emotion
3) hypnagogic hallucinations:
- dreal like vivid perceptions which occures at the onset of sleep and associated with fearfullness
- these occuring at the time of awakening r called as hypnopompic hallucinations
4) sleep paralysis:
- this occures either at awakening or at sleep onset
- person is concius bt unable to move his body
- episode last for 30 sec to few mins
Other associated symptoms r:
Fugue states, blackouts, blurring of vision,
Diagnosis: confirmed by polysomnography which shows decreased REM latency
Treatment:
- forced naps at regular times in the day
- stimulant medicatin e.g. Amphetamine or modafinil
- anti-depressants
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